Early Stage Technologies for Dermal and Transdermal Drug Delivery: Magnetophoresis and Electret
Macromolecules (>600Da) and hydrophilic molecules penetrate poorly across the skin due to the barrier function of the stratum corneum. Therefore, formulation scientists use chemical and physical permeation enhancers to enhance penetration. Researchers have investigated iontophoresis, electroporation, sonophoresis, microneedles, and laser-based techniques already as potential technologies for dermal and transdermal drug delivery. In addition, many interesting technologies are still in the early stage of development. Recently, scientists have studied novel technologies for cutaneous drug delivery.
This article provides a concise review of magnetophoresis and electret-mediated techniques.
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